Spinal Muscular Atrophy

Spinal Muscular Atrophy
Author : Charlotte J Sumner
Publisher : Academic Press
Total Pages : 506
Release : 2016-10-24
ISBN 10 : 9780128036860
ISBN 13 : 0128036869
Language : EN, FR, DE, ES & NL

Spinal Muscular Atrophy Book Description:

Spinal Muscular Atrophy: Disease Mechanisms and Therapy provides the latest information on a condition that is characterized by motoneuron loss and muscle atrophy, and is the leading genetic cause of infant mortality. Since the identification of the gene responsible for SMA in 1995, there have been important advances in the basic understanding of disease mechanisms, and in therapeutic development. This book provides a comprehensive accounting of recent advances in basic and clinical research that covers SMA clinical features and standards of care, multifaceted aspects of SMN protein functions and SMA disease pathology, various animal models, and biomarkers, as well as current therapeutic development. This title is ideal for graduate students/postdocs and principal investigators who are already in the SMA field and need to keep updated on recent findings and approaches, and for those who are new to, or would like to join, the field. Likewise, users will find an excellent source of reading for biotech/pharma scientists, clinical researchers, and practitioners, regulators, and patients and their advocacy organizations. Furthermore, this book is a handy reference for researchers and clinicians who may want to apply the research strategies and therapeutic approaches in SMA to other rare diseases. Provides comprehensive, up-to-date reviews by leading investigators on diverse topics of SMA, including clinical features and patient care, SMN genetics and protein functions, animal models, disease pathology and mechanisms, biomarkers, current therapeutic development, and the role of non-profit organizations in therapeutic development Written to bridge multiple disciplines and promote better communications among basic scientists, clinical researchers, and health care providers on the latest developments in SMA Includes outstanding questions and perspectives for future investigations and key references for additional detailed study

Spinal Muscular Atrophy
Language: en
Pages: 506
Authors: Charlotte J Sumner
Categories: Medical
Type: BOOK - Published: 2016-10-24 - Publisher: Academic Press

Spinal Muscular Atrophy: Disease Mechanisms and Therapy provides the latest information on a condition that is characterized by motoneuron loss and muscle atrop
Spinal Muscular Atrophy
Language: en
Pages:
Authors: Marc-Olivier Deguise
Categories:
Type: BOOK - Published: 2020 - Publisher:

Spinal muscular atrophy (SMA) is a devastating recessive neurological disorder thought to be affecting primarily the motor neurons. As such, paralysis, motor we
Spinal Muscular Atrophy: New Insights for the Healthcare Professional: 2011 Edition
Language: en
Pages: 20
Authors:
Categories: Medical
Type: BOOK - Published: 2012-01-09 - Publisher: ScholarlyEditions

Spinal Muscular Atrophy: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively
Spinal Muscular Atrophy
Language: en
Pages: 127
Authors: Bernard L. Maria
Categories:
Type: BOOK - Published: 2007 - Publisher:

It's One of Them!
Language: en
Pages: 184
Authors: Grace Saunders
Categories: Fiction
Type: BOOK - Published: 2014-12-10 - Publisher: AuthorHouse

Grace Saunders and her brother Ben were both born with the genetic disorder spinal muscular atrophy type 2/3, SMA. From her happy childhood growing up in Hertfo
Spinal Muscular Atrophy: New Insights for the Healthcare Professional: 2012 Edition
Language: en
Pages: 30
Authors:
Categories: Medical
Type: BOOK - Published: 2012-12-10 - Publisher: ScholarlyEditions

Spinal Muscular Atrophy: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively
Spinal Muscular Atrophy
Language: en
Pages: 179
Authors: Irena Hausmanowa-Petrusewicz
Categories: Children
Type: BOOK - Published: 1978 - Publisher:

Identification and Characterization of Spinal Muscular Atrophy (SMA) Modifiers - Insight from Cellular and Vertebrate Disease Models
Language: en
Pages:
Identification and Characterization of Spinal Muscular Atrophy (SMA) Modifiers - Insights from Cellular and Vertebrate Disease Models
Language: en
Pages: 170
The Role of Muscle and Nerve in Spinal Muscular Atrophy
Language: en
Pages: 193
Authors: Chitra C. Iyer
Categories:
Type: BOOK - Published: 2016 - Publisher:

Spinal Muscular Atrophy (SMA) is the leading genetic cause of infant death, affecting approximately 1 in 10,000 live births worldwide. SMA is caused due to decr